[GESIDA/GESITRA-SEIMC, PNS and ONT consensus document on solid organ transplant (SOT) in HIV-infected patients in Spain (March, 2005)].

نویسندگان

  • José M Miró
  • Julián Torre-Cisnero
  • Asunción Moreno
  • Montserrat Tuset
  • Carmen Quereda
  • Montserrat Laguno
  • Elisa Vidal
  • Antonio Rivero
  • Juan Gonzalez
  • Carlos Lumbreras
  • José A Iribarren
  • Jesús Fortún
  • Antonio Rimola
  • Antonio Rafecas
  • Guillermina Barril
  • Marisa Crespo
  • Joan Colom
  • Jordi Vilardell
  • José A Salvador
  • Rosa Polo
  • Gregorio Garrido
  • Lourdes Chamorro
  • Blanca Miranda
چکیده

Solid organ transplant may be the only therapeutic alternative in some HIV-infected patients. Experience in North America and Europe during the last five years shows that survival at three years after an organ transplant is similar to that observed in HIV-negative patients. The criteria agreed upon to select HIV patients for transplant are: no opportunistic infections (except tuberculosis, oesophageal candidiasis or P. jiroveci -previously carinii- pneumonia), CD4 lymphocyte count above 200 cells/.L (100 cells/.L in the case of liver transplant) and an HIV viral load which is undetectable or suppressible with antiretroviral therapy. Another criterion is a two-year abstinence from heroin and cocaine, although the patient may be in a methadone programme. The main problems in the post-transplant period are pharmacokinetic and pharmacodynamic interactions between antiretorivirals and immunosuppressors, rejection and the management of relapse of HCV infection, which is one of the main causes of post-liver transplant mortality. Up to now, experience with pegylated interferon and ribavirin is scarce in this population. The English version of the manuscript is available at http://www.gesidaseimc.com.

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Urinary tract infections (UTI) are one of the most common infections in solid organ transplant (SOT) recipients. A systematic review was performed to assess the management of UTI in SOT recipients. Recommendations are provided on the management of asymptomatic bacteriuria, and prophylaxis and treatment of UTI in SOT recipients. The diagnostic-therapeutic management of recurrent UTI and the role...

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عنوان ژورنال:
  • Enfermedades infecciosas y microbiologia clinica

دوره 23 6  شماره 

صفحات  -

تاریخ انتشار 2005